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  • The ASHD Program

    In 2016, the Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India launched a major project titled the ‘Accelerating the application of Stem cell technology in Human Disease’ or ASHD program. The program involves top Indian institutes – The Christian Medical College (CMC) with the Centre for Stem Cell Research (CSCR), a unit of inStem, at Vellore, the National Centre for Biological Sciences (NCBS), Institute for Stem Cell and Regenerative Medicine (inStem), and the National Institute for Mental Health and Neurosciences (NIMHANS) from Bangalore – in a giant collaborative effort to use stem cells in research, diagnostics and therapeutics. The ASHD program also partners with the Centre for iPS Cell Research and Application (CiRA), Kyoto University, Japan, which is led by Prof. Shinya Yamanaka, a leading pioneer in stem cell technology. The program at NCBS, inStem, and NIMHANS - The Accelerator program for Discovery in Brain disorders using Stem cells (ADBS) - involves research to understand mental illness by harnessing the power of sophisticated clinical investigations, modern human genetics, and stem cell technology. The program at CSCR / CMC - Novel Approaches to Hematological Diseases (NAHD) - involves developing modern methods including gene therapy for hereditary blood disorders such as hemophilia, thalassemia and sickle cell disease, all of which are causes of major morbidity and mortality in India. In order to have maximum impact on hereditary hemoglobin diseases in the population at risk, this initiative combines these efforts with a community outreach program for the control of major hemoglobin disorders.
  • The ASHD Program

    In 2016, the Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India launched a major project titled the ‘Accelerating the application of Stem cell technology in Human Disease’ or ASHD program. The program involves top Indian institutes – The Christian Medical College (CMC) with the Centre for Stem Cell Research (CSCR), a unit of inStem, at Vellore, the National Centre for Biological Sciences (NCBS), Institute for Stem Cell and Regenerative Medicine (inStem), and the National Institute for Mental Health and Neurosciences (NIMHANS) from Bangalore – in a giant collaborative effort to use stem cells in research, diagnostics and therapeutics. The ASHD program also partners with the Centre for iPS Cell Research and Application (CiRA), Kyoto University, Japan, which is led by Prof. Shinya Yamanaka, a leading pioneer in stem cell technology. The program at NCBS, inStem, and NIMHANS - The Accelerator program for Discovery in Brain disorders using Stem cells (ADBS) - involves research to understand mental illness by harnessing the power of sophisticated clinical investigations, modern human genetics, and stem cell technology. The program at CSCR / CMC - Novel Approaches to Hematological Diseases (NAHD) - involves developing modern methods including gene therapy for hereditary blood disorders such as hemophilia, thalassemia and sickle cell disease, all of which are causes of major morbidity and mortality in India. In order to have maximum impact on hereditary hemoglobin diseases in the population at risk, this initiative combines these efforts with a community outreach program for the control of major hemoglobin disorders.

Gene Therapy

The NAHD program envisages to develop novel methods for gene therapy of hereditary blood disorders such as hemophilia, thalassemia and sickle cell disease.

Applications of iPSC Technology

The NAHD program intends to create a bank of cells from individuals with homozygous HLA haplotype called the “haplobank” with an aim to develop the field of cell therapy.

Thalassaemia and Sickle Cell Disease Control Program

Under the NAHD program, CSCR and CMC, Vellore have taken initiative to develop a model for community outreach program for the control of major haemoglobin disorders.


Participating Institutes