ALOK SRIVASTAVA
Professor / Scientist
Centre for Stem Cell Research
Christian Medical College
Phone: Office:+91 416 2284102
Lab:
Fax: +91 416 2284103
Email: aloks@cmcvellore.ac.in
In the laboratory we are trying to extend the current understanding of haematopoietic stem cell niche to human diseases. The aim is to evaluate the components of the niche - haematopoietic, osteoblastic and endothelial, separately as well as in co-culture systems. Initially, it is planned to evaluate patients with bone marrow failure as well as leukemia’s after the methods are established.
Selected Recent Publication:
V. Mathews, B. George, E. Chendamarai, K M Lakshmi, S. Desire, P. Balasubramanian, A. Viswabandya, R. Thirugnanam, A. Abraham, R.V. Shaji, A. Srivastava, M. Chandy. Single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Long Term Follow Up Data. J Clin Oncol July 19, 2010.
Rajashekar R, Mathews V, Lakshmi ML, George B, Viswabandya A, Chandy M, Srivastava A. Cellular immune reconstitution and its impact on clinical outcome in children with beta thalassemia major undergoing a matched related myeloablative allogeneic bine marrow transplantation. Biol Blood Marrow Transplant. 2009; 15:597-609.
Mathews V, George B, Lakshmi KM, Viswabandya A, John JM, Sitaram U, Daniel D, Chandy M, Srivastava A. Impact of pretransplant splenectomy on patients with beta-thalassemia major undergoing a matched-related allogeneic stem cell transplantation. Pediatr Transplant. 2009;13:171-176.
Srivastava A. Gene therapy for hemophilia. J Thromb Haemost 2005; 3:1313.